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Their perturbations of mind exercised great influence over their bodies; and such was the anxiety and melancholy with which they were overwhelmed when they saw me involved in certain highly important lawsuits brought against me by men of power and position, and so great was their fear that I should lose, that they were seized with the humor of melancholy, of which the bodies of those who live irregularly are always full. This humor so embittered their lives, and grew upon them to such a degree, that it brought them to the grave before their time.

The triumph of epigenetic embryology in the 18th and 19th centuries was to be paralleled by dynamic theories of the evolution of species (instead of the traditional one-time creation) and by historical interpretations of human culture in terms of evolving stages of maturation. In the introduction to the Historia, in the crucial third paragraph, Bacon also presented a rationale for scientific intervention against aging. " But the structural elements, such as bone and connective tissue and "nearly all the organic parts," were considered by Bacon to be only "repaired with difficulty and loss" and hence fall into decay.

Thus, in 1960, Walt W. Rostow of MIT sketched a history of The Stages of Economic Growth. Despite the Cold War polemics that infused his interpretation, Rostow identified usefully, in the context of modernization theory, several key stages of development in the transition from economic scarcity to abundance. And in the 1970s, Fernand Braudel filled in some of the historical detail about the phase that Rostow had characterized breezily as the "take off," and the French historian even attempted to make estimates of the GNP and PCI (per capita income) for specified early chronological periods in Venetian and English development.

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