By John B. West

The heritage of high-altitude body structure and drugs is this kind of wealthy and colourful subject that it truly is marvelous nobody has undertaken a finished account prior to. From the early balloonists to numerous high-altitude expeditions, culminating within the nice feat of mountain climbing Mount Everest with out supplementary oxygen, the fundamental organic problem of hypoxia has underpinned the human event at excessive altitude. Of key value in different parts of drugs together with pulmonology, severe care, anesthesiology and cardiology, this subject is additionally of common curiosity to different lifestyles sciences corresponding to biology and ecology, simply because hypoxia is encountered via many organisms in the course of the animal kingdom.
High Life covers the subject from its earliest beginnings with the Greeks to the final or 3 years, and highlights many geographical destinations, resembling China, Japan, India and Russia. together with 185 illustrations, over 800 references, and 3 appendixes detailing the chronology of major occasions, databases of high-altitude guides, tables of high-altitude destinations, a listing of classical books at the subject and narratives of classical and sleek high-altitude expeditions, this publication is a accomplished reference textual content which could be of worth to an individual attracted to excessive altitude and hypoxia.

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He was thus able to study the effect of exposing blood to air while the blood passed through the lungs. Lower first demonstrated that the blood entering the lungs through the pulmonary artery was essentially the same as venous blood. He then showed that if the lungs were deprived of air by occluding the trachea, the blood that came from the cervical artery was as dark as that in the venous blood (Lower, 1669, pp. 164-165). He went on to show that if the blood was forced through the lungs when they were ventilated with fresh air, the blood was bright red even if the animal was already dead and there was no movement of the heart.

He produced "inflammable air" (hydrogen) by the action of acids on metals (as Boyle had done some 100 years before). " He communicated this finding to Cavendish who then burned large quantities of inflammable air and common air and obtained pure water. Furthermore, he showed that when one volume of dephlogisticated air and two volumes of inflammable air were mixed together and ignited, water was formed without any residue of gas. However, Cavendish again interpreted the results in terms of the phlogiston theory and concluded that Priestley's dephlogisticated air was actually dephlogisticated water.

There he developed a circle of friends who met regularly to discuss contemporary scientific topics. The group was known as The Invisible College and later became the Royal Society in 1662. Incidentally, Boyle was a patient of Harvey's because of his weak eyes. Boyle moved to Oxford in 1654, where he lived next to University College. He was one of the first of a remarkable group of physiologists known as the Oxford School, which included Robert Hooke, Richard Lower, and John Mayow. Boyle was extraordinarily versatile and applied himself to all branches of the natural sciences, making contributions in many.

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