By Edward L. Schneider and John W. Rowe (Eds.)

Meant for researchers and graduate scholars within the biology of growing old, this ebook offers a normal evaluate of biomedical gerontology and an replace to earlier variants. It makes a speciality of 3 significant assets of effect on getting old: organic, mental and social

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Extra resources for Handbook of the Biology of Aging

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1987). Nucleotide sequence structure and consistency Strain differences, chromosomal location, of a developmentally regulated DNA dele­ and loss during micronuclear aging. tion in Tetrahymena thermophila. MoMolecular and General Genetics, 197, 244lecular and Cellular Biology, 7, 435-443. 253. Allis, C. , Allen, R. , Wiggins, J. , Chi- Baba, M. , Darga, L. , 8k Czelusniak, f. (1981). Evolution of cytocoine, L. , & Richman, R. (1984). Prochrome C investigated by the maximum par­ teolytic processing of HI-like histones in simony method.

Ing the preceding cell cycle as cells become Allis, C. , 8k Wiggins, J. C. (1984b). His­ committed to cell division. Experimental tone rearrangements accompany nuclear dif­ Cell Research, 174, 355-366. ferentiation and dedifferentiation in Tetrahymena. Developmental Biology, 101, 282- Blackburn, E. , 8k Szostak, J. W. (1984). The molecular structure of centromeres and 294. changes in cell cycle timing could impair the proper targeting of chromatin molecules necessary for normal function. 8. The role of the environment on gene expression and longevity has been emphasized, especially with respect to hormesis, a beneficial response to low doses of an otherwise harmful agent.

2. The ciliary fibrous protein is capable of the typical 9 + 2 ciliary array (see text in Wichterman, 1986). 3. The phagocytic membrane can potentiate similar environmental interactions. 4. The cell membrane is an electrically excitable membrane like nerve and muscle cells (Kung, 1985; Kung &. Saimi, 1982). 5. Vertebrate hormones like insulin (Kohida, Thomka, &. Csaba, 1986) and neurotransmitters like serotonin, dopamine, and epinephrine stimulate cell responses in protozoa, for example, enhanced phagocytosis (Quinones-Maldonado &.

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