By Rajesh Pahwa, Kelly E. Lyons Ph.D.

Highly counseled, BMA clinical booklet Awards 2014

This quantity has lengthy prevailed as one of many best assets on Parkinson's ailment (PD). absolutely up to date with useful and fascinating chapters on pathology, neurochemistry, etiology, and step forward examine, this resource spans each crucial subject regarding the identity, evaluate, and remedy of PD.

Reflecting the various advances that experience taken position within the administration of PD, this quantity promotes a multidisciplinary method of care and offers new sections at the most recent pharmacologic, surgical, and rehabilitative cures, in addition to crucial diagnostic, imaging, and nonmotor administration strategies.

New to this edition:

• Early id of premotor indicators
• capability ailment amendment brokers
• actual and occupational therapy

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Additional info for Handbook of Parkinson's Disease, Fifth Edition

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63. Lerner MR, Goldman RS. Skin colour, MPTP, and Parkinson’s disease. Lancet 1987; 2:212. 64. McInerney-Leo A, Gwinn-Hardy K, Nussbaum RL. Prevalence of Parkinson’s disease in populations of African ancestry: a review. J Natl Med Assoc 2004; 96(7):974–979. 65. Mayeux R, Marder K, Cote LJ, et al. The frequency of idiopathic Parkinson’s disease by age, ethnic group, and sex in Northern Manhattan, 1988–1993. Am J Epidemiol 1995; 142:820–827. 66. Schoenberg BS, Osuntokun BO, Adejua AOG, et al. Comparison of the prevalence of Parkinson’s disease in black populations in the rural United States and in rural Nigeria: door-to-door community studies.

Drachman DA, Long RR, Swearer JM. Neurological evaluation of the elderly patient. In: Albert ML, Knoefel JE, eds. Clinical Neurology of Aging. 2nd ed. New York: Oxford University Press, 1994:159–180. qxd 7/2/07 7:27 PM Page 25 Epidemiology 25 3. Rajput AH. Clinical features of tremor in extrapyramidal syndromes. In: Findley LJ, Koller WC, eds. Handbook of Tremor Disorders. , 1994: 275–291. 4. Rajput A, Robinson C, Rajput AH. Longitudinal study of essential tremor: 21 autopsy cases. Neurology 2004; 62:932–936.

As discussed previously, incidence has remained relatively constant but life expectancy has increased; one would then expect overall crude prevalence rates to have increased over time. GENDER AND PARKINSONISM The available evidence indicates that men have a slightly higher risk of parkinsonism than women, with the exception of drug-induced parkinsonism (59,60). 5% (61). Suggested reasons for this risk included differential exposure to external risk factors, an X-linked genetic factor, and mitochondrial dysfunction.

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