By Steven G. Gabbe MD, Jennifer R. Niebyl MD, Joe Leigh Simpson MD, Mark B Landon MD, Henry L Galan MD, Eric R. M. Jauniaux MD PhD FRCOG, Deborah A Driscoll MD, Vincenzo Berghella MD, William A Grobman MD MBA

After 30 years, Obstetrics: basic and challenge Pregnancies remains your go-to selection for authoritative guidance on handling today’s obstetric sufferer. International specialists put the latest wisdom during this area of expertise at your fingertips, with present and suitable info on every little thing from fetal origins of grownup sickness, to bettering international maternal well-being, to special themes in daily obstetrical perform. Highly readable, well-illustrated, and simple to understand, this bestselling obstetrics reference is a perfect software for citizens and clinicians.

  • Take benefit of the collective knowledge of world specialists within the box,
  • including new editors― Drs. Vincenzo Berghella and William Grobman -- and approximately 30 new participants.

  • Gain a brand new perspective 
  • on a variety of modern day key issues - all evidence-based and straightforward to learn.

  • Sweeping updates throughout
  • together with 4 new chapters: ‘Vaginal beginning after Cesarean Delivery’; ‘Placenta Accreta’; ‘Obesity’; and ‘Improving international Maternal health and wellbeing: demanding situations and Opportunities’

  • 11 videos
  • toughen bankruptcy content material and improve studying in parts comparable to cesarean supply and operative vaginal supply

  • New
  • Glossary of the main usually used key abbreviations for simple reference

  • Expanded use of bolded statements and key points in addition to extra tables, circulation diagrams, and bulleted lists enables and enhances the mastery of every chapter
  • More than a hundred pictures within the Obstetrical Ultrasound bankruptcy offer a major source for regular and irregular fetal anatomy

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Additional info for Gabbe: Obstetrics - Normal and Problem Pregnancies

Example text

Placental estradiol modifies metabolism and production of corticoids and progesterone. [177] , [178] This effect occurs by modulation of maternal cortisol across the placenta into the fetus. [169] At least three factors are involved. Fetal adrenal mass increases with advancing gestation[154] , [155] (Fig. 1-19B) . [178] [179] [180] [181] [182] Rapid growth that begins at approximately the 10th week of gestation consists almost entirely of enlargement of the fetal zone [178] , [179] (Fig. 1-22) (Figure Not Available) .

215] The ovaries continue to be a significant source of 17-hydroxyprogesterone throughout pregnancy. During the third trimester, however, the placenta uses fetal 5-sulfoconjugated precursors to secrete increasing amounts of 17-hydroxyprogesterone. 5 ng/ml during the follicular phase of normal menstrual cycles. In conceptual cycles, 17-hydroxyprogesterone concentrations rise to about 1 ng/ml on the day of the LH peak, fall slightly for about 1 day, rise again over the subsequent 4 to 5 days to a level of 1 to 2 ng/ml, and then increase gradually to a mean of approximately 2 ng/ml (luteal phase levels) at the end of 12 weeks.

78] Transforming Growth Factor-. [55] , [108] Epidermal Growth Factor. EGF is synthesized by the syncytiotrophoblast, and EGF receptors are observed Figure 1-13 (Figure Not Available) Maternal serum concentrations of immunoreactive CRH in 256 individual pregnant women in relation to gestational age and postpartum (mean ±SD). (Modified from Stalla GK, Bost H, Stalla J, et al: Human corticotropin releasing hormone during pregnancy. ) 14 Figure 1-14 Geometric mean (67 percent confidence intervals) for plasma concentrations of inhibin.

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