By Robert A. Bonomo, Marcelo E. Tolmasky

Antibiotic-resistant micro organism, or "superbugs," current an more and more lethal hazard to human healthiness. With chapters from the world's prime researchers and students during this box, this entire quantity is a crucial and well timed evaluate of this severe subject.

summary:

This e-book offers a state of the art evaluation of the mechanisms of resistance. The enzymes and enzyme platforms distinctive during this paintings contain these enthusiastic about genetic reorganization, antibiotic Read more...

Show description

Read or Download Enzyme-mediated resistance to antibiotics : mechanisms, dissemination, and prospects for inhibition PDF

Similar viral books

Tularemia - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

It is a 3-in-1 reference publication. It provides a whole clinical dictionary protecting thousands of phrases and expressions with regards to tularemia. It additionally supplies vast lists of bibliographic citations. ultimately, it presents details to clients on the best way to replace their wisdom utilizing a number of web assets.

Toxocara: the enigmatic parasite

This booklet includes 19 chapters targeting Toxocara and the disorder it motives referred to as toxocariasis. The chapters are divided into the subsequent components: molecular biology (3 chapters); Toxocara as a version procedure (2); animal versions for toxocariasis (1); human ailment (4); immunology of toxocariasis (2); epidemiology of toxocariasis (3); Toxocara within the veterinary context (3); financial effect of the affliction (1).

Antimicrobial Chemotherapy

Antimicrobial brokers are crucial for the remedy of life-threatening infections and for dealing with the weight of youth infections in the neighborhood. additionally, they play a key function in organ and bone marrow transplantation, melanoma chemotherapy, man made joint and center valve surgical procedure. in contrast to different sessions of medications, they're susceptible to resistance from mutations in objective microorganisms, and their hostile results could expand to different sufferers (increased chance of cross-infection).

Oxford handbook of infectious diseases and microbiology

Totally reviewed and revised for its moment variation, the Oxford instruction manual of Infectious illnesses and Microbiology keeps its place because the must-have advisor to all points of infectious ailments and microbiology. Reflecting the present method of joint postgraduate education programmes, the instruction manual takes an built-in method of either matters.

Extra resources for Enzyme-mediated resistance to antibiotics : mechanisms, dissemination, and prospects for inhibition

Sample text

44. Ogle, J. , D. E. Brodersen, W. M. Clemons, M. J. Tarry, A. P. Carter, and V. Ramakrishnan. 2001. Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science 292:897–902. 45. , and Y. Suzuki. 1965. Chloramphenicol-, dihydrostreptomycin-, and kanamycin-inactivating enzymes from multiple drug-resistant Escherichia coli carrying episome ‘R’. Nature 208:1301–1303. 46. , D. Gur, S. Unal, and G. H. Miller. 2001. The changing nature of aminoglycoside resistance mechanisms and prevalence of newly recognized resistance mechanisms in Turkey.

Antimicrob. Agents Chemother. 13:41–48. Waksman, S. , and H. A. Lechevalier. 1949. Neomycin, a new antibiotic active against streptomycin-resistant bacteria, including tuberculosis organism. Science 109:305–307. , Q. Vicens, and E. Westhof. 1999. Aminoglycoside-RNA interactions. Curr. Opin. Chem. Biol. 3:694–704. White, D. , and P. F. McDermott. 2001. Emergence and transfer of antibacterial resistance. J. Dairy Sci. 84(Suppl. E): E151–E155. Williams, J. , and D. B. Northrop. 1978. Kinetic mechanisms of gentamicin acetyltransferase I.

Sherratt, and M. E. Tolmasky. 2003. The aminoglycoside 6p-N-acetyltransferase type Ib encoded by Tn1331 is evenly distributed within the cell’s cytoplasm. Antimicrob. Agents Chemother. 47:2897–2902. Donabedian, S. , L. A. Thal, E. Hershberger, M. B. Perri, J. W. Chow, P. Bartlett, R. Jones, K. Joyce, S. Rossiter, K. Gay, J. Johnson, C. Mackinson, E. Debess, J. Madden, F. Angulo, and M. J. Zervos. 2003. Molecular characterization of gentamicin-resistant enterococci in the United States: evidence of spread from animals to humans through food.

Download PDF sample

Rated 4.28 of 5 – based on 12 votes