By Roy Jones
St. Martin's health facility, bathtub, united kingdom.
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14 Teunisse S, Derix MMA, van Crevel H. Arch Neuroll991; 48: 274-7. 15 Gelinas I, Auer S. Functional autonomy. In: Gauthier S, ed. Clinical Diagnosis and Management of Alzheimer’s Disease. London: Martin Dunitz, 1996: 191-9. 16 Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging ofdementia. BrJPsychiatry 1982; 140: 566-72. 17 Morris JC. The CDR current version and scoring rules. Neurology 1993; 43: 2412-14. 18 Reisberg B, Ferris SH, deLeon MJ, Crook T. The global deterioration scale for assessment of primary degenerative dementia.
Regulatory authorities appear to have defined a clinically significant response as an improvement of at least 4 points on the ADAS-Cog particularly if accompanied by an improvement (score c 4) on a global rating such as the CIBIC-Plus or at least no deterioration on the CIBIC-Plus and the ADL assessment. A 4-point decline on ADAS-Cog is roughly the decline expected in untreated patients over 6 months, although, as will be seen from Chapter 4, placebo groups in clinical trials have often shown a smaller decline than this.
Close your eyes' 011 wr/ting Write a short sentence 011 Copying Copy this drawing (two intersecting pentagons). All 10 angles must be present and the intersection should form a quadrangle 011 Total score Maximum 30 The benefits of druq treatment 27 There has been considerable debate about how it should be performed and scored. There are no parallel forms although alternative words can be chosen for the registratioidrecall items (apple, table and penny are usually used but other words have included ball, flag, tree, shirt, brown, honesty, lemon, key and balloon).