Drawing jointly contributions from a various crew of foreign specialists within the box, this choice of papers examines the biology and pathology of elastin on the molecular point. themes contain the constitution, ultrastructure and serve as of elastin; elastin rules; elastin's position in getting older, lung improvement and disorder and atherosclerosis; in addition to comparable facets of pharmacology and meals.

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Extra resources for Ciba Foundation Symposium 192 - The Molecular Biology and Pathology of Elastic Tissues

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Nature 246:461466 Hoeve CAJ, Flory PJ 1974 Elastic properties of elastin. Biopolymers 13:677-688 Jacob MP, Hornebeck W, Robert L 1983 Studies on the interaction of cholesterol with soluble and insoluble elastin. Int J Biol Macromol 5275-278 Leahy D, Hendrickson W, Aukhil I, Joshi P, Erickson HP 1992 X-ray crystal structure and cell adhesion studies of the RGD-containing FN I11 domain from tenascin. -spiral conformations of the elastomeric polytetrapeptides, (VPGG), and (IPGG),, by 2D NMR, and molecular mechanics studies.

4. The elastic fiber. FASEB J 7:1208-1218 Ross R, Fialkow PJ, Altman L K 1977 The morphogenesis of elastic fibers. Adv Exp Biol Med 79:7-17 Sakai LY, Keene DR, Engvall E 1986 Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils. J Cell Biol 103:2499-2509 Shimada T , Sato F, Zhang L, Ina K, Kitamura H 1993 Three-dimensional visualization of the aorta and elastic cartilage after removal of extracellular ground substance with a modified NaOH maceration method. J Electron Microsc 421328-333 Smith P 1976 A comparison of the orientation of elastin fibers in the elastic laminae of the pulmonary trunk and aorta of rabbits using the scanning electron microscope.

Biochim Biophys Acta 310:48 1-486 Tamburro AM, Guantieri V, Pandolfo L, Scopa A 1990 Synthetic fragments and analogues of elastin. 11. Conformational studies. Biopolymers 29:855-870 30 Discussion Tillinghast EK, Townley MA 1986 The independent regulation of protein synthesis in the major ampullate glands of Araneus caraticus (keyserling). J Insect Physiol32: 117123 Trinick J 1992 Understanding the functions of titin and nebulin. FEBS Lett 307:44-48 Urry DW, Starcher B, Partridge SM 1969 Coacervation of solubilized elastin effects a notable conformational change.

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