By Serge Gauthier, Pedro Rosa-Neto

Dementia is among the best demanding situations dealing with the clinical career because the inhabitants a while. exact analysis is key as many rarer sorts of the sickness are treatable if well-known early. This choice of case reports from all over the world illustrates either universal and weird motives of dementia, emphasizing medical reasoning, integrative pondering and problem-solving talents. each one case involves a scientific background, exam findings and specific investigations, by means of prognosis and dialogue. the purpose is to enhance diagnostic talents via cautious research of person offering styles, and to lead therapy judgements, utilizing state of the art diagnostic class and instruments. The reader may be capable of distinguish sufferers who want reassurance, nearer follow-up or fast referral to really expert companies. Written and edited via the world over famous specialists in dementia, those case reports will tell and problem clinicians in any respect phases in their careers.

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Extra info for Case Studies in Dementia: Common and Uncommon Presentations (Case Studies in Neurology)

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She had severe impairment of novel problem solving, hypothesis testing, and mental flexibility with severe perseveration. She demonstrated difficulty in the acquisition of new material, but adequate retention of information once learned. Hand–eye co-ordination and fine motor movements were moderately impaired 29 Case 4 in the dominant hand and severely impaired in the non-dominant hand. There was no apraxia. Her score on a measure of overall knowledge and everyday judgment was average, but insight into her cognitive deficits was limited.

Research into predictive factors for progression to dementia in SCI is extensive. Increase of theta power in baseline EEG in SCI subjects has been shown to predict decline or conversion to MCI and dementia. , 2010). o. the DESCRIPA study. , 2009). , 2004). Although in MCI patients MTA predicted conversion to AD, this has not been determined yet in SCI. FDG-PET in SCI subjects demonstrated hypometabolism in the parietotemporal regions and the parahippocampal gyrus with lower metabolic rates in the latter region in APOE ε4 positive subjects.

The onset of dementia is insidious in over half of the patients and the course is usually continuous and slowly progressive. The clinical symptoms are usually low mental speed, extrapyramidal symptoms (rigidity, hypokinesia), bilateral pyramidal symptoms (short steps, vivid reflex activity in the legs), and positive masseter reflex. Other neurological signs are imbalance and falls, urinary frequency and incontinence, dysarthria, and dysphagia. Behavioral and psychiatric symptoms include depression, personality change, emotional lability, emotional bluntness, and mental slowness.

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