By Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Mario Ulises Pérez-Zepeda
This ebook reports classical epidemiological and scientific examine reports, with a spotlight on getting older. Chapters hide methodological subject matters just like the clinical process, ethics, and the results of sure exclusion standards and the paintings contains a examine scientific strategies like multi morbidity, frailty and performance. The authors display the problems and demanding situations for researchers of age and getting older, and likewise think of the interpretation of medical wisdom, from uncomplicated to scientific and from medical to public regulations of social and well-being care.
The specialize in getting older is what supplies this e-book its invaluable point of view on learn technique. All authors have significant event in getting older, geriatrics or gerontology and every bankruptcy contains either a theoretical framework and functional examples of experiences in getting older. Readers will observe research designs which are reviewed for simple constitution, major flaws and merits and are analyzed for particular stipulations and variables concerning aging.
This textual content is suited for either wellbeing and fitness care execs taking good care of older adults and researchers who're new to investigate in getting older. it's appropriate around the disciplines, together with medication, psychology, social sciences and dentistry and it helps studying with graphs and figures.
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Extra info for Aging Research - Methodological Issues
Unlike prevalence studies, case studies may have a follow-up on the subject to learn the nature of the illness described; this aspect is shared in the case series design. In the example chosen to illustrate a case study from the set of older adults, a case is described of systemic lupus erythematosus accompanied by primary biliary cirrhosis . The illness in other age groups is not common, and much less so in older adults, so that in the description of the particular characteristics found, new knowledge from the case may be learned.
Globally multiple investigations in the biomedical area are trying to identify the molecular, genetic, genomic, transcriptomic and proteomic factors (among others) involved in the aging process, in order to be translated into an adequate health status for an aging population. However, most studies have low power to detect small changes in relation to age in animal models or in humans. This raises the emerging need for studies to increase the power and contemplate the effect of the interaction of multiple factors in the aging process.
Ann N Y Acad Sci 1067:120–128. 015 34. Partridge L (2011) Some highlights of research on aging with invertebrates, 2010. Aging Cell 10(1):5–9. x 35. Edwards C, Canfield J, Copes N, Brito A, Rehan M, Lipps D et al (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet 16(1):8. 1186/s12863-015-0167-2 36. Rogina B (2011) For the special issue: aging studies in Drosophila melanogaster. Exp Gerontol 46(5):317–319. 001 37. Katewa SD, Kapahi P (2011) Role of TOR signaling in aging and related biological processes in Drosophila melanogaster.